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Scientific Publications
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Sickle Cell Disease
Our Lead
Scientific Publications
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Date
Publication
There are currently no publications.
Prior Publication
Date
Publication
May 2023
X-ray crystallography and sickle cell disease drug discovery-a tribute to Donald Abraham
(Donkor et al.)
February 2023
Modulating hemoglobin allostery for treatment of sickle cell disease: current progress and intellectual property
(Pagare et al.)
November 2020
VZHE-039, a novel antisickling agent that prevents erythrocyte sickling under both hypoxic and anoxic conditions
(Abdlulmalik et al.)
October 2018
Rational modification of vanillin derivatives to stereospecifically destabilize sickle hemoglobin polymer formation
(Deshpande et al.)
October 2011
Crystallographic analysis of human hemoglobin elucidates the structural basis of the potent and dual antisickling activity of pyridyl derivatives of vanillin
(Abdulmalik et al.)
September 2008
Pyridyl derivatives of benzaldehyde as potential antisickling agents
(Nnamani et al.)
February 2005
5-hydroxymethyl-2-furfural modifies intracellular sickle haemoglobin and inhibits sickling of red blood cells
(Abdulmalik et al.)
September 2004
Structural basis for the potent antisickling effect of a novel class of five-membered heterocyclic aldehydic compounds
(Safo et al.)